For people with diabetes, healthcare providers usually consider blood sugar levels above 180 mg/dL to be high blood sugar (hyperglycemia) . However, most people with diabetes don’t feel symptoms of high blood sugar until their level is 250 mg/dL or higher. A blood sugar reading of 300 mg/dL or more can be dangerous, and if you have two readings in a row of 300 or more, you should call your doctor. A reading above 300 mg/dL can also be life-threatening, and immediate medical attention is necessary.