There are several over-the-counter medicines that can help with a runny nose. Antihistamines such as chlorpheniramine, diphenhydramine, loratadine, and cetirizine can block histamine production for allergy-related runny noses
. Decongestants such as oxymetazoline, phenylephrine, and pseudoephedrine can curb swelling inside the nose and sinuses, and help you breathe more easily
. Topical anticholinergics, such as ipratropium bromide nasal spray, may also help reduce a runny nose, but this medicine requires a prescription from a doctor
. It is important to check with a doctor before taking any medicine to make sure they will work well with other medicines you may be taking. Additionally, some traditional remedies such as drinking plenty of liquids, including chicken soup, and trying a saltwater nasal rinse may also help relieve common cold discomfort
