The organelle that protects DNA is the nucleus. The nucleus is a membrane- bound organelle found in eukaryotic cells that houses and safeguards the cell's DNA. It is enclosed by the nuclear envelope, a double membrane that isolates the DNA from the cytoplasm, protecting it from damage and interference. This compartmentalization allows control over DNA replication and gene expression. The nucleus also contains nuclear pores that regulate the transport of molecules in and out, maintaining DNA integrity and cellular function.