The amount of nicotine in a cigarette can vary depending on factors such as the brand of the cigarette, the type of tobacco used, and how it was processed. However, on average, a single cigarette contains about 10 to 12 mg of nicotine. It is important to note that not all of the nicotine in a cigarette is inhaled, and an average smoker inhales about 1.1 to 1.8 milligrams of nicotine per cigarette, equating to 22 to 36 milligrams per pack of 20 cigarettes. It is also worth mentioning that e-cigarettes have differing levels of nicotine depending on the brand, and the amount of nicotine in a vape can be much higher than in a cigarette.