According to multiple sources, Matthew Perry, who played Chandler Bing on Friends, has been open about his struggles with drugs and alcohol. Perrys changing appearance throughout the 10 seasons of Friends serves as a dead giveaway for which drugs he was using at the time. Perry writes in his memoir, "Friends, Lovers and the Big Terrible Thing," that "You can track the trajectory for my addiction if you gauge my weight from season to season. When I’m carrying weight, it’s alcohol; when I’m skinny, it’s pills. When I have a goatee, it’s lots of pills". By the end of the third season of Friends, Perry was trying to obtain 55 Vicodin a day. Perrys addiction spanned throughout his time on Friends, which ran between 1994 and 2004.
Therefore, it can be concluded that Chandler was on drugs throughout the seasons of Friends, and Perrys changing appearance throughout the show can be used to track his addiction.