The backflow of blood in the heart is prevented by various structures, primarily valves. In the right side of the heart, the tricuspid valve prevents backflow of blood from the right ventricle to the right atrium. In the left side of the heart, the mitral valve (or bicuspid valve) prevents backflow of blood from the left ventricle to the left atrium, and the aortic valve prevents backflow of blood into the left ventricle. These valves ensure that blood flows in only one direction, effectively preventing backflow