As of late September 2025, the NFL teams that remain undefeated in the 2025 season are the Buffalo Bills and the Philadelphia Eagles. Both teams have a 4-0 record. Earlier in Week 4, there were six undefeated teams, including the Indianapolis Colts, San Francisco 49ers, Los Angeles Chargers, and Tampa Bay Buccaneers, but after Week 4 games, the Colts and 49ers also lost, bringing the number of undefeated teams down to just the Bills and Eagles. The Eagles are defending Super Bowl champions and have won against tough teams including the Chiefs, Rams, and Buccaneers, while the Bills have maintained momentum with notable wins such as a close game against Baltimore and a victory over the New Orleans Saints. Thus, only the Buffalo Bills and Philadelphia Eagles are undefeated at 4-0 in the 2025 NFL season currently.
