The internal temperature of cooked chicken should reach 165°F (74°C) for food safety, according to the USDA. This temperature should be measured using an instant-read food thermometer, inserted in different spots, making sure to pay special attention to the chicken breasts and thighs which are the thickest parts of the meat. The cooking time and temperature can vary depending on the method of cooking and the size of the chicken pieces. For example, bone-in chicken will take longer to reach the desired internal temperature, while smaller cuts will require less cooking time. It is important to ensure that the chicken is cooked to the proper temperature to avoid the risk of salmonella and other foodborne illnesses.