After taking misoprostol, you can expect cramping and bleeding to start within 1-4 hours. It is normal to see large blood clots (up to the size of a lemon) . You may feel tired or crampy for a day or so, and you’ll have bleeding and spotting for a while. Most people go back to normal activities the day after a medication abortion, but it is recommended to plan on resting and being in a comfortable place on the day you take misoprostol. You should avoid hard work or heavy exercise for several days. After your abortion is complete, cramping and bleeding should lighten up as the hours and days go by. You may also have tender breasts, and they may leak a milky discharge, but that should stop in a couple of days. Any chills, fevers, or nausea you have should go away pretty quickly, but if you have nausea, vomiting, diarrhea, or a fever for more than 24 hours after taking misoprostol, you should call your doctor or health center right away as it could be a sign of an infection. Your doctor or health care center staff will give you written after-care instructions and a phone number you can call with any questions about abortion pill side effects or any other concerns.