when did vaccines start

Vaccines started with the first scientifically tested method by Edward Jenner in 1796. Jenner developed the first vaccine against smallpox by using material from cowpox sores, which he inoculated into a young boy, successfully demonstrating immunity to smallpox. This event marks the beginning of vaccination as a scientific practice. Before Jenner, variolation (deliberately exposing people to smallpox to induce immunity) was practiced but was risky. Jenner's cowpox-based vaccine laid the foundation for modern vaccination and has since evolved to include vaccines for many other diseases.