The Indianapolis Colts' next game is on December 22, 2025, against the San Francisco 49ers.
Upcoming Schedule
Their home game at Lucas Oil Stadium kicks off at 8:15 PM ET and will air on ESPN.
Following that, the Colts host the Jacksonville Jaguars on December 28, 2025, at 1:00 PM ET on FOX.
The Week 18 matchup at Houston is scheduled for January 4, 2026, with time still TBA.
