when proteins are denatured, which type of bond is not disturbed?

When proteins are denatured, the primary structure is not disturbed. Specifically, the covalent peptide bonds that hold the sequence of amino acids together in the primary structure remain intact during denaturation. The denaturation process disrupts the secondary, tertiary, and quaternary structures of the protein, which depend on weaker bonds such as hydrogen bonds, ionic bonds, and Van der Waals interactions. However, the stronger covalent peptide bonds in the primary structure are not broken by denaturation conditions like heat, pH changes, or chemicals unless harsh conditions specifically target these bonds. Thus, the type of bond that is not disturbed during protein denaturation is the covalent peptide bond.