The best time to take vitamin B12 is generally in the morning, ideally on an empty stomach. Taking it early in the day helps you feel more energized throughout your waking hours since B12 supports energy metabolism and brain function. It is absorbed best when stomach acid levels are optimal, typically in the morning. Taking B12 late in the day might interfere with sleep for some sensitive individuals because of its activating effects. For optimal absorption, it is recommended to take B12 supplements either half an hour before a meal or at least 2 hours after eating. Drinking water with the supplement also helps absorption. If taking B12 on an empty stomach causes nausea, it can be taken with a meal. In summary:
- Take vitamin B12 in the morning
- Best on an empty stomach (30 minutes before or 2 hours after food)
- Avoid taking it late in the day to prevent sleep disruption
- If stomach upset occurs, take with food
This timing allows you to maximize the energy and neurological benefits of vitamin B12 while aligning with your body's natural rhythm.
