Statins should generally be taken once a day, and for some types, the timing depends on the specific statin medication. Short-acting statins like simvastatin, pravastatin, lovastatin, and fluvastatin are most effective when taken in the evening because cholesterol production in the body peaks at night. Long-acting statins such as atorvastatin and rosuvastatin can be taken at any time of day, as their levels stay effective throughout the day. The key is to take the statin consistently at approximately the same time each day. It is best to follow a doctor's specific advice on timing and dosage, as some statins may have particular instructions.
Statins are usually prescribed for adults aged 40 to 75 with one or more cardiovascular risk factors and a certain level of cardiovascular disease risk to prevent primary cardiovascular events. However, specific recommendations about when to start taking statins depend on one's health status and risk factors and should be guided by medical professionals.