where does fermentation occur

17 minutes ago 1
Nature

Fermentation occurs in the cytoplasm of cells, in the absence of oxygen. It is a metabolic pathway used by many microorganisms (and some animal cells under anaerobic conditions) to convert sugars into energy and byproducts such as lactic acid or ethanol. Key points

  • Location: cytoplasm of the cell (both prokaryotes and eukaryotes).
  • Oxygen requirement: anaerobic conditions; fermentation proceeds without oxygen.
  • Cellular context: follows glycolysis; pyruvate is diverted to fermentation instead of entering mitochondria for aerobic respiration.
  • Common outputs:
    • Lactic acid fermentation: lactate as the end product (in muscles and some bacteria).
* Alcoholic fermentation: ethanol and CO2 as end products (yeast, many fungi).
  • Purpose: regenerates NAD+ to sustain glycolysis under anaerobic conditions and provides a quick source of ATP, though less efficiently than aerobic respiration.

If you’d like, I can tailor this to a specific organism (e.g., human muscle cells vs. yeast) or explain how fermentation differs from anaerobic respiration in more detail.