In Oblivion Remastered, you can cure disease in several ways:
- Pray at an Altar of the Nine : Each major city has a Great Chapel with an Altar of the Nine. Interacting with the altar will instantly cure your diseases for free without using Magicka. For example, the Great Chapel of Mara in Bravil has such an altar
- Purchase and cast the Cure Disease spell : You can buy the Journeyman-level Restoration spell "Cure Disease" from priests at the Great Chapels throughout Cyrodiil, such as Trevaia at the Chapel of Dibella in Anvil or Isa Raman at the Great Chapel of Talos in Bruma. Casting this spell cures all diseases on yourself
- Drink Cure Disease potions : These can be bought from alchemists or crafted using ingredients like Mandrake Root, Clannfear Claws, Elf Cup Cap, and others. Mandrake Root can be found in ingredient shops or gathered near Skingrad and along roads past Bravil. Drinking such potions cures disease instantly
- Eat specific foods or ingredients : Eating items like Mandrake Root or Shepherd's Pie also cures diseases, including early vampirism stages
To summarize, the easiest and most accessible method is to visit a Great Chapel in any major city and pray at the Altar of the Nine to cure diseases immediately. Alternatively, buying or crafting Cure Disease potions or spells provides flexibility if you are far from a chapel or want to cure diseases on the go
