Testosterone is typically injected intramuscularly (IM) into one of the following sites:
- Gluteus Maximus (Buttocks): The preferred and most comfortable site for many people. The injection is given in the upper outer quadrant of the buttock, away from the spine, to avoid nerves and blood vessels such as the sciatic nerve
. This site is recommended for injections like Testosterone Undecanoate and is considered safe with minimal discomfort
- Vastus Lateralis (Thigh): This site is often chosen for self-injection because it is easy to see and access. The injection is given in the outer middle third of the thigh, which you can find by dividing the thigh horizontally into three equal parts and aiming for the outer middle section
. Some find this site slightly more uncomfortable than the glute but easier to manage themselves.
Additional notes:
- The injection should be given at a 90-degree angle deep into the muscle
- For safety, avoid injecting in the same spot repeatedly to prevent pain and scarring
- Subcutaneous injections (just under the skin) can be done in the belly fat area, but testosterone is most commonly given intramuscularly
- When injecting in the buttocks, care must be taken to avoid the superior gluteal artery and sciatic nerve
In summary, the two main recommended sites for intramuscular testosterone injections are the upper outer quadrant of the buttocks (gluteus maximus) and the outer middle third of the thigh (vastus lateralis)
. The choice depends on personal preference, comfort, and whether someone else is administering the injection.
