The sugars that are converted to glucose in the liver include primarily fructose and galactose. After absorption, most fructose and almost all galactose are rapidly converted into glucose in the liver through enzymatic processes. This conversion ensures that glucose is the main sugar form transported to tissues for energy use. Specifically, the liver has enzymes that convert fructose into intermediates that feed into gluconeogenesis or glycolysis pathways, leading to glucose production. Similarly, galactose is also converted into glucose derivatives in the liver. Therefore, among common dietary sugars, fructose and galactose are converted to glucose in the liver, while glucose itself is directly utilized.
