John Cena most recently lost to Gunther in his WWE retirement match at Saturday Night's Main Event on December 13, 2025, where he tapped out to a sleeper hold.
Notable Past Losses
Cena has had several high-profile defeats throughout his WWE career, often against top competitors in major events.
- Gunther (2025) : Ended Cena's in-ring career via submission in Washington, D.C.
- Solo Sikoa (Crown Jewel 2023) : A surprising loss to the young Bloodline member.
- Kevin Owens (Elimination Chamber 2015) : Shocking debut win for Owens on the main roster.
- CM Punk (Money in the Bank 2011) : Iconic 34-minute WWE Championship match in Chicago.
- The Rock (WrestleMania 2012-2013) : Interference-led losses in high-stakes "Once in a Lifetime" bouts.
- Brock Lesnar (SummerSlam 2014) : Brutal squash match for the WWE World Heavyweight Championship.
These losses, while infrequent given Cena's dominant record, marked pivotal storyline moments.
