The Los Angeles Rams have lost to the following teams in the 2025 NFL season so far:
- Philadelphia Eagles
- San Francisco 49ers
Most recently, they lost an overtime game at home against the San Francisco 49ers. The 49ers were dealing with injuries but still managed to upset the Rams. The kicker Joshua Karty had kicking struggles that affected the outcome. Prior to that, the Rams also lost to the Philadelphia Eagles earlier in the season.
