The killers in the Scream movies, known as "Ghostface," vary by installment:
- In the original Scream (1996), the killers are Billy Loomis and Stu Macher.
- Scream 2 featured killers Mickey Altieri and Nancy Loomis.
- Scream 3's killer was Roman Bridger.
- Scream (2022) revealed Sam Carpenter's boyfriend Richie Kirsch and Tara's friend Amber Freeman as killers.
- Scream VI (2024) had multiple killers: Jason Carvey, Detective Wayne Bailey, and his children Quinn Bailey and Ethan Landry.
Each set of killers has their own motives and connections to the main characters or previous murders in the franchise. For example, in Scream VI, Detective Bailey and his children commit murders tied to a family vendetta and legacy of killings, while in earlier movies the killers are often connected by personal relationships and revenge schemes involving Sidney Prescott and others.
