The Arizona Cardinals' starting running back for the 2025 season was James Conner, a veteran in his fifth season with the team, who had consecutive 1,000-yard rushing seasons in 2023 and 2024. However, Conner suffered a season-ending ankle injury early in the 2025 season. After Conner's injury, Trey Benson, who was expected to be the backup and a significant contributor, was also placed on injured reserve due to a knee issue, sidelining him for at least four to six weeks. With both Conner and Benson out, Emari Demercado has stepped into the primary running back role. Michael Carter and Zonovan Knight are also part of the running back group and are expected to see playing time, with Carter likely handling the majority of early-down carries and Demercado focusing on third-down and passing situations. Bam Knight is another option as a powerful back who may get opportunities. In summary, the Cardinals have shifted to a running back rotation led currently by Emari Demercado, with Michael Carter and Bam Knight as key contributors behind him for the 2025 season due to injuries to Conner and Benson.
