The Philadelphia Phillies will enter the 2025 playoffs with a first-round bye, meaning they skip the Wild Card round and will start in the National League Division Series (NLDS). They have secured at least the No. 2 seed in the NL and home-field advantage in the NLDS. The exact opponent depends on the outcome of the Wild Card round matchups.
- If the Phillies finish as the No. 2 seed, they will face the winner of the No. 3 vs. No. 6 Wild Card game, which currently projects to be the Los Angeles Dodgers vs. the New York Mets.
- If they finish as the No. 1 seed, they will face the winner of the No. 4 vs. No. 5 matchup, likely the Chicago Cubs vs. the San Diego Padres.
The Phillies will host Games 1 and 2 of the NLDS at Citizens Bank Park on October 4 and October 6, with subsequent games on the road starting October 8.