The starting running back (RB) for the Arizona Cardinals as of early October 2025 is expected to be Emari Demercado. This is due to injuries to their primary RBs: James Conner is out for the season with a foot injury, and Trey Benson was placed on injured reserve with a knee injury. As a result, Demercado, along with Michael Carter and Bam Knight, will handle the running back duties, with Demercado likely taking the lead role, especially in inside carries and a bigger share of snaps. Head coach Jonathan Gannon expressed confidence in Demercado and Carter stepping up to compete for the position, with Demercado poised to lead the backfield starting in the upcoming games.
