The San Francisco 49ers won against the Los Angeles Rams in overtime with a final score of 26-23. The game was held on October 2, 2025, and was marked by a tough battle where the 49ers, despite being short-handed, managed a crucial defensive stop on a fourth-and-1 late in the overtime to secure the victory. The game featured key plays including a 41-yard field goal in overtime by Eddy Piñeiro for the 49ers and a late rally by the Rams that tied the game before overtime.
