The San Francisco 49ers won the game against the Los Angeles Rams with a final score of 26-23 in overtime on October 2, 2025. The 49ers secured their victory with a key defensive stop on fourth-and-1 in overtime, preventing the Rams from converting and ending the game. Eddy PiƱeiro kicked crucial field goals, including one in overtime, and Mac Jones led the team despite injuries. This win snapped the 49ers' three-game losing streak against the Rams and improved their record to 4-1.
