The San Francisco 49ers won their game against the Los Angeles Rams with a close 26-23 victory in overtime on October 2, 2025. Backup quarterback Mac Jones led the short-handed 49ers, throwing for 342 yards and two touchdowns despite missing several key players. The game was decided by a defensive stop on a crucial fourth-and-1 play in overtime, preserving the 49ers' win at SoFi Stadium. This victory improved the 49ers' record to 4-1 for the season.
