The San Francisco 49ers won their game against the Los Angeles Rams on October 2, 2025, with a thrilling 26-23 victory in overtime. The game featured a strong performance from quarterback Mac Jones, who passed for 342 yards and two touchdowns despite playing with a leg injury. The 49ers overcame significant injuries and key player absences to secure the win with a critical defensive stop on a fourth-and-1 play in overtime. Eddy Piñeiro's field goals, including a 41-yard kick in overtime and a 59-yard kick late in the fourth quarter, were decisive in the victory. The Rams had a chance to win but were stopped by the 49ers' defense in the final moments of overtime.
