It is generally safe to drink alcohol while taking amoxicillin, as alcohol does not directly interfere with the antibiotic's effectiveness. However, health professionals usually recommend avoiding alcohol to allow the body the best chance to fight the infection. Drinking alcohol can worsen side effects like nausea, dizziness, and stomach upset, and may slow down the healing process by weakening the immune system and causing dehydration. Therefore, moderation or avoiding alcohol while on amoxicillin is advisable for optimal recovery.