It is generally not recommended to drink alcohol while taking antibiotics because alcohol can increase side effects like nausea, dizziness, and stomach upset, and potentially decrease the effectiveness of some antibiotics. Drinking alcohol while on antibiotics may also hinder the immune system and prolong recovery. However, moderate alcohol consumption (e.g., one drink for women, two for men) is considered safe with many—but not all—antibiotics. Certain antibiotics, such as metronidazole, tinidazole, and others, can cause severe reactions if combined with alcohol and should be avoided entirely during treatment. It is best to follow the advice of your prescribing doctor or pharmacist about alcohol use with specific antibiotics and typically wait 48 to 72 hours after finishing antibiotics before drinking any alcohol.
Risks of Drinking Alcohol on Antibiotics
- Increased side effects: Alcohol can intensify common antibiotic side effects such as dizziness, drowsiness, nausea, vomiting, and headaches.
- Reduced antibiotic effectiveness: Alcohol may interfere with how the body absorbs or metabolizes some antibiotics, potentially making them less effective.
- Impaired recovery: Alcohol weakens the immune system and leads to dehydration, making it harder to recover from infection.
Antibiotics That Must Not be Mixed With Alcohol
- Metronidazole (Flagyl)
- Tinidazole (Tindamax)
- Linezolid (Zyvox)
- Cefotetan and Ceftriaxone
- Trimethoprim-sulfamethoxazole (Bactrim)
- And others listed by healthcare providers
Recommendations
- Avoid alcohol entirely if your antibiotic warns against it.
- If moderate drinking is permitted, keep it minimal and stay aware of side effects.
- Wait at least 48 to 72 hours after completing antibiotics before consuming alcohol.
- Consult your doctor or pharmacist for guidance specific to your antibiotic.
In summary, drinking alcohol while on antibiotics is best avoided to ensure effectiveness of the medication and minimize side effects, with some antibiotics requiring complete abstinence during the course of treatment.
