Yes, it is safe to eat Spam straight out of the can. Spam is fully cooked during the production process inside the sealed can, which eliminates bacteria and other potential contaminants. The airtight packaging along with preservatives like sodium nitrite keep it safe for consumption without any additional cooking. Many people eat it directly from the can, especially in situations like camping or emergencies where cooking might not be feasible. Just make sure the can is not damaged, bulging, or expired before consuming it. However, some prefer cooking Spam for better flavor and texture, but eating it uncooked is perfectly safe.