The most expensive thing in the world is the International Space Station (ISS), which cost about $150 billion to develop and build. It is a massive international scientific project orbiting Earth, making it the most costly object ever created. Other extremely expensive items include the James Webb Space Telescope at $10 billion, the Large Hadron Collider at $9 billion, and the ultra-luxury History Supreme Yacht valued at approximately $4.8 billion, the latter being the most expensive luxury collectible item due to its gold and platinum design and rare materials. These items stand out because of their advanced technology, massive scale, rarity, or cultural significance.
In the realm of materials, antimatter is by far the most expensive substance, costing approximately $59.8 trillion per gram, although it is not a purchasable object like the others.