Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. There are various treatments available for alopecia areata, including natural ingredients, medications, and clinical trials. Here are some details on each:
Natural Ingredients
- Azelaic acid
- Peppermint oil
- Pumpkin seed oil
- Garlic supplements/shampoo
- Black castor oil
- Jojoba oil
- Argan oil
A 2020 systematic review found that these natural ingredients have been used in the treatment of alopecias, with an emphasis on central centrifugal cicatricial alopecia.
Medications
- Ritlecitinib: Pfizer announced positive top-line results from a Phase 2b/3 trial of ritlecitinib in alopecia areata in 2021. The trial met the primary efficacy endpoint of improving scalp hair regrowth. Ritlecitinib is not yet approved by the FDA for the treatment of alopecia areata.
- Olumiant: Olumiant is an FDA-approved medication for the treatment of rheumatoid arthritis that has also been used off-label for alopecia areata.
Clinical Trials
- PF-06651600: This is an investigational study drug that has been evaluated in a global Phase 2b/3 study for the treatment of alopecia areata. The study evaluated the safety and effectiveness of PF-06651600 in adults and adolescents with 50% or greater scalp hair loss. The study was completed in 2021, but the drug is not yet approved by the FDA for the treatment of alopecia areata.
Its important to note that while some treatments may work for some people, they may not work for others. Its best to consult with a healthcare professional to determine the best treatment plan for each individual case.
