Fluconazole is an antifungal medication used to treat various fungal infections including candidiasis. Fluconazole tablets are available in 50 mg, 100 mg, 150 mg, or 200 mg strengths. The active ingredient in fluconazole is 2,4-difluoro-α,α1-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol, and the molecular formula is C13H12F2N6O with a molecular weight of 306.3. The tablets also contain inactive ingredients such as microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C Red No. 40 aluminum lake dye, and magnesium stearate. The capsule forms of fluconazole often contain lactose, and the powder form lists sucrose as an ingredient. Fluconazole is metabolized minimally in the liver and is excreted in urine and sweat.
Positive effects of fluconazole include its ability to inhibit the growth of the yeast Candida albicans, which is most commonly responsible for vaginal yeast infections. However, fluconazole can also have negative effects, such as the potential for development of resistance to the medication. Patients with impaired renal function are at risk of overdose.
Ingredients or materials in fluconazole tablets include:
- Fluconazole USP
- Microcrystalline cellulose
- Dibasic calcium phosphate anhydrous
- Povidone
- Croscarmellose sodium
- FD&C Red No. 40 aluminum lake dye
- Magnesium stearate
Ingredients or materials in fluconazole capsules include:
- Fluconazole
- Colloidal silicon dioxide
- D&C Red No. 6 Lake
- Dibasic calcium phosphate anhydrous
- FD&C Red No. 40 Lake
- Magnesium stearate
- Microcrystalline cellulose
- Sodium lauryl sulfate
- Sodium starch glycolate
Ingredients or materials in fluconazole powder include:
- Fluconazole
- Lactose (in capsule forms)
- Sucrose (in powder form)
