Melatonin is a hormone naturally produced by the body, and its levels naturally increase during pregnancy. Research suggests that melatonin supplementation might be safe during pregnancy under medical supervision, but there is insufficient definitive research to confirm its safety for all pregnant women. Some healthcare professionals may recommend melatonin for specific pregnancy-related conditions like preeclampsia or in women trying to conceive, but for healthy pregnant women, melatonin supplementation is generally not advised due to the unknown risks and potential excessive melatonin exposure. Because over-the-counter melatonin supplements are not strictly regulated, the exact dosage can vary, which adds to the uncertainty of its safety during pregnancy. Non-drug interventions such as cognitive behavioral therapy for insomnia and good sleep hygiene are often preferred for managing sleep difficulties in pregnant women. If melatonin supplementation is considered necessary, it should only be done under direct supervision and guidance from a healthcare provider. In summary, while melatonin is naturally present and plays roles in pregnancy, taking melatonin supplements during pregnancy is generally not recommended without medical advice due to limited research on safety and potential risks to the fetus.