It is generally advised to avoid drinking alcohol while taking Diflucan (fluconazole). Alcohol can interfere with the metabolism of the medication in the liver, potentially reducing its effectiveness and increasing the risk of side effects such as nausea, dizziness, stomach upset, and liver strain. Combining alcohol with Diflucan may also exacerbate side effects and put extra stress on the liver, which could lead to liver damage, especially for those with pre-existing liver conditions. It is best to consult a healthcare provider for personalized advice, but caution and avoidance of alcohol while on Diflucan therapy is the safest approach.
Some sources mention that having a single drink might not cause severe interactions, yet medical guidance generally errs on the side of avoiding alcohol altogether during treatment to ensure safety and optimal effectiveness of the medication.
