can you take antihistamines when pregnant

It is generally considered safe to take certain antihistamines during pregnancy, but the choice of which antihistamines to use is important. First- generation antihistamines such as chlorpheniramine, hydroxyzine, and dexchlorpheniramine are among the safest options and have been used for a long time with reassuring data on their safety during pregnancy. However, these are sedating and may have anticholinergic side effects. Second-generation antihistamines, such as loratadine and cetirizine, are also commonly recommended, especially after the first trimester, as they are non-sedating and have not been found to be teratogenic in studies. Both loratadine and cetirizine are pregnancy category B agents, indicating no evidence of risk in humans. It is generally advised to avoid systemic antihistamines, if possible, particularly in the first trimester when organ development occurs, and to prefer topical treatments for mild symptoms initially. Importantly, any use of antihistamines in pregnancy should be under the guidance of a healthcare provider, weighing the benefits and risks, and monitoring for any changes such as reduced fetal movements or contractions. Staying well-hydrated is also advised to counteract side effects. In summary, while many antihistamines are safe to use during pregnancy, particularly first-generation agents and some second-generation ones like loratadine and cetirizine, consultation with a healthcare professional is essential before use. Avoidance in the first trimester and preference for topical treatments is recommended when possible.