Yes, you can use nail polish remover on gel nails. Most professional gel nail polish removers contain high concentrations of acetone, which is the most effective ingredient for removing gel nail polish. However, acetone can be harsh and drying for the skin, so it is important to use it with caution and avoid getting it on your skin. There are different types of gel nail polish removers available on the market, including pure acetone liquid remover, foil remover wraps, nail drill machine, burst-on magic remover, and remover cream. Some gel nail remover creams are gentle and non-irritating, and they have no damage to nails and skin. If you prefer non-toxic and natural options, there are also non-acetone polish removers that use less aggressive solvents like ethyl acetate, isopropyl alcohol, and propylene carbonate, and they add moisturizing agents like glycerin, panthenol, and soy to minimize the drying effect. You can also make your own DIY nail polish remover using acetone or other ingredients like rubbing alcohol, vinegar, and lemon juice.