diflucan dosage review

11 months ago 40
Nature

Diflucan is an antifungal medication that is available in different dosage forms and strengths. The daily dose of Diflucan should be based on the infecting organism, severity of the fungal infection, and the patients response to therapy. The following are the available dosage forms and strengths of Diflucan:

  • Injection solution: 2mg/mL
  • Oral suspension: 10mg/mL - 40mg/mL
  • Tablet: 50mg - 100mg - 150mg - 200mg

Diflucan Tablets contain fluconazole as the active ingredient and the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C Red No. 40 aluminum lake dye, and magnesium stearate. Diflucan for Oral Suspension contains fluconazole and the following inactive ingredients: sucrose, sodium citrate dihydrate, citric acid anhydrous, sodium benzoate, titanium dioxide, colloidal silicon dioxide, xanthan gum, and natural orange flavor.

Diflucan capsules contain lactose monohydrate, and patients with rare hereditary problems of galactose intolerance, the total lactase deficiency, or glucose-galactose malabsorption should not take this medicine. The capsules also contain less than 1 mmol sodium (23 mg) per capsule, which is essentially sodium-free.

There are some interactions with other medications that should be avoided when taking Diflucan. For example, fluconazole will increase the level or effect of flibanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism, and coadministration of flibanserin with moderate or strong CYP3A4 inhibitors is contraindicated. Diflucan and ibutilide both increase QTc interval, and their concomitant use is contraindicated. Diflucan and indapamide both increase QTc interval, and their concomitant use is contraindicated.

In summary, Diflucan is an antifungal medication that is available in different dosage forms and strengths. The daily dose of Diflucan should be based on the infecting organism, severity of the fungal infection, and the patients response to therapy. Diflucan capsules contain lactose monohydrate, and patients with rare hereditary problems of galactose intolerance, the total lactase deficiency, or glucose-galactose malabsorption should not take this medicine. There are some interactions with other medications that should be avoided when taking Diflucan.