The general rule of thumb is to apply serum before moisturizer. Serum is a lightweight formula that contains a high concentration of active ingredients that penetrate the skin deeply. On the other hand, moisturizer is a thicker formula that helps to lock in moisture and protect the skin's barrier. Applying serum first allows the active ingredients to penetrate the skin and work their magic, while applying moisturizer after helps to seal in the benefits and provide hydration.
It is important to note that the order of application may vary depending on the specific products being used. When in doubt, it is best to follow the instructions provided by the manufacturer.