Ephedrine is a compound that can powerfully stimulate the nervous system and heart. It is an alpha- and beta-adrenergic agonist and a norepinephrine-releasing agent. It is used for its vasoconstrictive, positive chronotropic, and positive inotropic effects. Ephedrine sulfate injection is indicated in the treatment of allergic disorders, such as bronchial asthma, and as a central nervous system stimulant in narcolepsy and depressive states. Ephedrine hydrochloride tablets are indicated for the treatment or prevention of attacks of bronchospasm in asthma.
Positive effects:
- Vasoconstrictive effects
- Positive chronotropic effects
- Positive inotropic effects
- Relaxation of bronchioles
Negative effects:
- Hypersensitivity to the active substance or to any of the excipients listed in section 6.1
- Ischaemic heart disease
- Hypertension
- Thyrotoxicosis
- Prostatic hypertrophy
- Ephedrine has positive inotropic and chronotropic effects on the heart and its use should be avoided in patients with ischaemic heart disease.
Ingredients or materials:
- Ephedrine sulfate injection, 5 mg/mL is a clear, colorless, sterile, ready-to-use solution for intravenous injection. Each mL contains ephedrine sulfate 5 mg (equivalent to 3.8 mg ephedrine base), sodium chloride 9 mg, and sodium hydroxide and/or acetic acid for pH adjustment, if necessary.
- Ephedrine hydrochloride tablets contain 15mg of ephedrine hydrochloride and 22.00mg of lactose.
