fluconazole review

11 months ago 48
Nature

Fluconazole is an antifungal medication that is available in tablet and capsule form. It is used to treat various fungal infections, including candidiasis. The tablets and capsules contain different amounts of fluconazole, ranging from 50 mg to 200 mg. The following inactive ingredients are present in fluconazole tablets: microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C Red No. 40 aluminum lake dye, and magnesium stearate. Fluconazole capsules contain sulfites and sugars as lactose, and the capsule shells are made of gelatin. The capsule forms of fluconazole often contain lactose and should not be administered with hereditary galactose intolerance, Lapp lactase enzyme deficiency, or malabsorption of glucose/galactose. The powder form, used for the oral suspension, lists sucrose as an ingredient and should not be used in patients who have been diagnosed with fructose, glucose/galactose malabsorption, and sucrase-isomaltase enzyme deficiency. There is no information regarding cross-hypersensitivity between fluconazole and other azole antifungal agents. Fluconazole is found in human breast milk at concentrations similar to plasma, so nursing mothers should limit exposure.