Prednisone dosing frequency varies by condition, severity, and patient factors, typically ranging from once daily to divided doses up to four times a day.
Short-Term Use
Lower doses (5-60 mg daily) are often taken once in the morning with food to mimic natural cortisol rhythms. Higher doses may split into 2-4 doses throughout the day.
Long-Term Use
Maintenance doses (5-20 mg daily) usually occur once daily or as alternate-day dosing to minimize side effects. Tapering is essential when stopping after 1+ weeks.
Key Warnings
Always follow a doctor's prescribed schedule, as self-adjusting risks withdrawal or adrenal issues. Children's doses are weight-based and determined individually.
