Neosporin is generally considered safe for dogs when used sparingly on minor wounds. However, it should be applied carefully in small amounts because ingesting large quantities (by licking the ointment) can cause gastrointestinal issues like vomiting or diarrhea. Some dogs might also be allergic to its ingredients, causing redness, swelling, or itching at the application site. To prevent licking, using a cone or bandaging the area is recommended. Veterinarians often advise consulting them before using Neosporin on dogs, especially if the wound is deep, bleeding heavily, or shows signs of infection, because Neosporin is not formulated specifically for dogs and can carry risks like allergic reactions, antibiotic resistance, and delayed healing. In cases of ingestion or adverse reactions, prompt contact with a vet is important for appropriate care. In summary, Neosporin can be used safely on dogs with caution and veterinary guidance for minor wounds but is not generally recommended for all cases without professional advice.