Product Details:
- Itraconazole is an azole antifungal agent used to treat serious fungal or yeast infections.
- It is available in different forms, including capsules, oral solution, and tablets.
- The capsules contain 100 mg of itraconazole coated on sugar spheres (composed of sucrose, maize starch, and purified water) .
- Inactive ingredients in the capsules include hard gelatin capsule, hypromellose, polyethylene glycol (PEG) 20,000, titanium dioxide, FD&C Blue No. 1, FD&C Blue No. 2, D&C Red No. 22, and D&C Red No. 28.
- Itraconazole has a molecular formula of C35H38Cl2N8O4 and a molecular weight of 705.64. It is a white to slightly yellowish powder. It is insoluble in water, very slightly soluble in alcohols, and freely soluble in dichloromethane.
Positive:
- Itraconazole exhibits in vitro activity against Blastomyces dermatitidis, Histoplasma capsulatum, Histoplasma duboisii, Aspergillus flavus, Aspergillus.
Negative:
- Itraconazole may cause side effects such as nausea, vomiting, diarrhea, headache, and dizziness.
- It may also interact with other medications, including antacids, stomach medicine, and certain soft drinks.
Ingredients or Materials:
- Active ingredient: itraconazole.
- Inactive ingredients in the capsules: hard gelatin capsule, hypromellose, polyethylene glycol (PEG) 20,000, titanium dioxide, FD&C Blue No. 1, FD&C Blue No. 2, D&C Red No. 22, and D&C Red No. 28.
- Other ingredients in Sporanox capsules: non-pareil beads, macrogol, and hypromellose. The capsule is made of gelatin and also contains titanium dioxide, indigo carmine.
- Safety data sheet for itraconazole lists it as a toxic product.
