Mounjaro is a once-weekly non-insulin injection used to improve blood sugar (glucose) levels in adults with type 2 diabetes mellitus. It works by activating the two different receptors GIP and GLP-1, which are natural incretin hormones that help regulate blood sugar levels. Mounjaro is not a weight loss drug. However, clinical trials have shown that people who do not have diabetes but do have elevated body mass indexes (BMI) lost considerable weight when they used Mounjaro. Although the FDA has not approved Mounjaro for weight loss yet, results from clinical trials have been positive, so it may be approved for weight loss in the future. In the Phase 3 SURMOUNT-1 72-week clinical trials, the mean Mounjaro weight loss was 15% for the 5mg dose, 19.5% for the 10mg dose, 20.9% for the 15mg dose, and 3.1% for placebo. Mounjaro (active ingredient tirzepatide) is a GLP-1 and GIP receptor agonist, meaning it mimics the activity of these hormones, which leads to weight loss.
Ingredients or materials: The active ingredient in Mounjaro is tirzepatide.
Positive: Mounjaro has been shown to lead to weight loss when used to treat patients with type 2 diabetes, alongside diet and exercise.
Negative: Mounjaro is expensive and may be hard to get. Like Wegovy and Ozempic, Mounjaro can cause unpleasant gastrointestinal side effects. Mounjaro is not for use in people with type 1 diabetes. It is not known if Mounjaro can be used in people who have had pancreatitis. Do not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called MTC or if you have an endocrine system condition called MEN 2, or if you have had a serious allergic reaction to tirzepatide or any of the ingredients in Mounjaro.
In summary, Mounjaro is a non-insulin injection used to improve blood sugar levels in adults with type 2 diabetes mellitus. Although it is not a weight loss drug, clinical trials have shown that it can lead to significant weight loss. Mounjaro contains the active ingredient tirzepatide and can cause unpleasant gastrointestinal side effects. It is not for use in people with type 1 diabetes or those who have had pancreatitis or certain types of thyroid cancer.
