Ketoconazole shampoo is a medicated shampoo designed to treat fungal infections affecting the scalp, such as stubborn dandruff and seborrheic dermatitis. It is available both over the counter (OTC) and by prescription from a healthcare provider. Different types of ketoconazole shampoos are available OTC and by prescription, with OTC ketoconazole shampoos containing 1 percent or less of ketoconazole. The most commonly known OTC brand is Nizoral, which is available in most supermarkets and online for purchase. Prescription brands include Ketozal, Ketozolin, and Ket Med.
The active ingredient in ketoconazole shampoo is ketoconazole, which is a broad-spectrum synthetic antifungal agent. The shampoo also contains other ingredients such as sodium laureth sulfate, disodium laureth sulfosuccinate, cocamide diethanolamide, hydrochloric acid, PEG-120 methyl glucose dioleate, imidurea, sodium chloride, sodium hydroxide, fragrance, and purified water. Inactive ingredients in Nizoral A-D Ketoconazole Anti-Dandruff Shampoo include acrylic acid polymer (carbomer 1342), butylated hydroxytoluene, cocamide MEA, FD&C Blue #1, fragrance, glycol distearate, and polyquaternium-7.
According to anecdotal evidence, ketoconazole shampoo may also help promote hair growth or reduce hair loss. However, if ketoconazole shampoo doesn’t work for your skin condition, you might try other alternatives, like other medications such as oral antifungals, to help you treat your overall condition or more widespread infections.
It is important to note that ketoconazole has a moderate concern for endocrine disruption and high concern for use restrictions, according to the EWG Skin Deep ingredient hazard score.