It is generally advised to avoid drinking alcohol while taking antibiotics. Although moderate alcohol consumption does not interfere with most antibiotics' effectiveness, alcohol can increase the risk of side effects like nausea, dizziness, and stomach upset. It may also weaken the immune system and delay recovery from infection. Some antibiotics, such as metronidazole and tinidazole, can cause severe reactions when mixed with alcohol and require complete avoidance. Waiting at least 48 to 72 hours after finishing antibiotics before drinking alcohol is recommended, especially for antibiotics with longer clearance times. Consulting a healthcare provider about specific antibiotics and alcohol use is essential for safety and effective treatment.
Risks of Mixing Alcohol and Antibiotics
- Increased side effects like nausea, vomiting, dizziness, and headaches
- Reduced effectiveness of certain antibiotics due to impaired absorption or metabolism
- Slower recovery from infection because alcohol weakens the immune response and causes dehydration
- Dangerous reactions with specific antibiotics (e.g., metronidazole causes flushing, rapid heartbeat, severe nausea)
Antibiotics That Should Not Be Mixed with Alcohol
- Metronidazole
- Tinidazole
- Linezolid
- Cefotetan and Ceftriaxone
- Doxycycline
- Erythromycin
- Rifampin
- Trimethoprim-sulfamethoxazole
Best Practice
Avoid alcohol during antibiotic treatment and for at least 2-3 days after completing the course. Always follow your prescribing doctor’s guidance regarding alcohol use with antibiotics.
