tesofensine side effects review

Tesofensine is a potential weight loss medication that is currently undergoing clinical trials. It is a pre-synaptic reuptake inhibitor of dopamine, serotonin, and noradrenaline, which helps to reduce hunger and decrease snacking. While tesofensine has shown promise in helping people lose weight, it does have some potential side effects. The most commonly reported side effects include dry mouth, headache, nausea, insomnia, diarrhea, and constipation. Other potential side effects may include increased heart rate or palpitations, changes in blood pressure or pulse rate, anxiety or agitation, depression, hallucinations, mania or psychosis, and seizures. A dose-dependent pattern was observed for dry mouth and insomnia. Blood pressure and heart rate increases with the therapeutically relevant doses of tesofensine (0.25 mg and 0.5 mg) were 1–3 mmHg and up to 8 bpm, respectively. In some cases, long-term use of tesofensine can also lead to an increased risk of heart attack or stroke. It is essential for individuals considering tesofensine as a treatment option to consult with healthcare professionals and undergo thorough medical evaluations. Finally, if any severe symptoms occur while taking tesofensine, it is important to seek medical attention immediately.