Two of the most memorable characters created by John Steinbeck are George Milton and Lennie Small from his novella "Of Mice and Men." George is small, quick-witted, and protective, while Lennie is physically large, mentally vulnerable, and has a childlike innocence. Their friendship and contrasting personalities are central to the story's emotional impact. Lennie's immense strength combined with his mental fragility, along with George's loyalty and internal conflict, make these characters iconic for their realism and complexity. Another highly memorable character is Tom Joad from Steinbeck's "The Grapes of Wrath." Tom is a symbol of resilience and solidarity during the hardships of the Great Depression, known especially for his powerful declaration "I'll be there." Additionally, Ma Joad, with her unwavering strength and determination to hold her family together, is also unforgettable. Other notable characters include Doc from "Cannery Row," an enigmatic and compassionate figure, and Cathy Ames from "East of Eden," complex and chilling in her manipulative darkness. Thus, George Milton, Lennie Small, Tom Joad, and Ma Joad stand out as some of Steinbeck's most enduring and memorable characters for their vivid, flawed, and deeply human portrayals.